Lyvewell

Glycine

Inhibitory neurotransmitter that lowers core body temp before sleep.

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Primary benefits

  • Faster sleep onset
  • Improved sleep quality
  • Glutathione precursor

How to take it

Dosing range

3000–5000 mg

Timing

before bed

Interactions & contraindications

Avoid if:

  • · None significant

Drug interactions:

  • · Clozapine

Always consult a healthcare provider before starting any new supplement, especially if you take prescription medications.

Research citations

  1. [1]The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus

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The Science of Glycine and Deep Sleep

Glycine is an amino acid that has emerged as a powerful sleep aid, with clinical studies showing it can improve sleep quality, increase time spent in deep sleep, and help you fall asleep faster.

Dr. Sarah ChenApr 25, 2026